Metabolomic Study in Huntington's Disease (METABO-HD)

Inclusion Criteria: For all groups: * age between 20 and 70 years * signature of the informed consent * covered by social security For presymptomatic group: * positive genetic test with CAG repeat length ≥ 37 in HTT gene * Unified Huntington Disease Rating Scale ≤ 5 For symptomatic group: * positive genetic test with CAG repeat length ≥ 37 in HTT gene * The Unified Huntington's Disease Rating Scale motor score ≥ 6 * The Total Functional Capacity score ≥ 11 Exclusion Criteria for all groups: * participation in another therapeutic trial (3 months exclusion period) * pregnancy and breastfeeding * persons deprived of their liberty by judicial or administrative decision