This study evaluates the effect of anxiety drugs taken at night on the ability to drive a car the next day. Participants will receive alprazolam, placebo, or zolpidem at night before bed or in the morning before using a driving simulator to assess impairment.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
OTHER
Masking
NONE
Enrollment
15
2mg alprazolam administered at night, placebo administered in the morning.
1mg alprazolam administered at night, placebo administered in the morning.
0.5mg alprazolam administered at night, placebo administered in the morning.
Center on Drug and Alcohol Research
Lexington, Kentucky, United States
Standard Deviation of Lane Position (SLDP)
Lane deviation (swerving) on a driving simulator. This is measured as the distance (cm) the driver deviates from the lane.
Time frame: 16 hours
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10mg alprazolam administered at night, placebo administered in the morning.
Placebo administered at night, placebo administered in the morning.
Placebo administered at night, 1mg alprazolam administered in the morning.