P- Maxillary alveolar cleft defects I- Platelet-rich fibrin (PRF) combined with biphasic calcium phosphate (BCP) C- Autogenous bone graft O- Outcome measure : bone height, bone volume, hospital stay, operation duration T- 6 months S- Randomized controlled clinical trial this study aimed to answer a clinical question whether the use of Platelet-rich Fibrin (PRF) combined with Biphasic Calcium Phosphate (BCP), can be an alternative to autogenous bone graft in reconstruction of alveolar cleft defect in maxillary arch.
this study aimed to answer a clinical question whether the use of Platelet-rich Fibrin (PRF) combined with Biphasic Calcium Phosphate (BCP), can be an alternative to autogenous bone graft in reconstruction of alveolar cleft defect in maxillary arch
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
18
Platelet rich fibrin combined with biphasic calcium phosphate(experimental group)
Bone obtained from the same individual who receiving the graft
Faculty of Dentistry, Cairo University
Cairo, Egypt
bone height
the vertical bone height measured from the most coronal level of the pyriform aperture to the most apical level of the bony bridge.
Time frame: six months postoperative.
bone volume
V= (A1xT) + ( A2 xT) + …….+ (An xT) where: V= volume A= area T= thickness of the axial C.T slice N=number of slices
Time frame: six months postoperative.
operation duration
It is the time elapsed between using the scalable for incision and the last stitch. It will be measured by watch in hours.
Time frame: within 4 hours ( the actual number of hours will be determined intra-operative )
hospital stay
Number of days that patients spend in hospital. Measured by calendar, starting from time of admission ending with time of discharge
Time frame: within 7 days
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