Effect of Oxytocin Infusion on Blood Loss During Abdominal Myomectomy

Kanuni Sultan Suleyman Training and Research Hospital100 enrolled

Overview

To evaluate the effects of oxytocin infusion during abdominal myomectomy.

Myomectomy is indicated for symptomatic uterine fibroids. Fibroids have blood supply and 20% of the abdominal myomectomy cases might require blood transfusion because of the nature of the surgery. Oxytocin infusion is one of the intervention to decrease blood loss during myomectomy. To evaluate the effects and benefits of oxytocin infusion during abdominal myomectomy we decide to conduct this randomized study.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

DOUBLE

Enrollment

100

Conditions

Myomectomy

Interventions

OxytocinDRUG

Patients will receive intravenous oxytocin infusion just before the surgery after the induction of general anesthesia.

salineOTHER

Patients will receive intravenous normal saline infusion just before the surgery after the induction of general anesthesia.

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 50 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age 18-50 * Patients who are candidate for abdominal myomectomy Exclusion Criteria: * History of previous myomectomy. * Suspected malignancy * Patients with preoperative anemia * Patients using hormonal treatments before the surgery.

Locations (1)

Kanuni Sultan Suleyman Egitim ve Arastırma Hastanesi

Istanbul, Turkey (Türkiye)

Outcomes

Primary Outcomes

Blood loss during surgery

estimated blood loss during the surgery measured by aspiration fluid.

Time frame: 2 hours

Secondary Outcomes

Blood loss after abdominal myomectomy

change in Hematocrit Percentage (before and after the surgery)

Time frame: 1 hour postoperatively

Data from ClinicalTrials.gov

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