Intracoronary Stenting and Antithrombotic Regimen: Lesion Platelet Adhesion as Selective Target of Endovenous Revacept

Inclusion Criteria: * Signed written informed consent * Men and women \>18 years of age * Diagnosis: Clinically stable coronary artery disease * Angiographic evidence of coronary artery disease * Indication for PCI Exclusion Criteria: * WOCBP who are unwilling or unable to use an acceptable method to avoid pregnancy for up to 4 weeks after receiving investigational product. * Women who are pregnant or breastfeeding or are planning pregnancy during course of trial * Women with a positive pregnancy test on enrolment or prior to investigational product administration. * Patients with elevated high sensitivity cardiac troponin T levels at screening * Patients receiving antithrombotic therapy with Prasugrel or Ticagrelor within 7 days prior to randomisation * History of hypersensitivity, contraindication or serious adverse reaction to any component of the study drug (GPVI-Fc, sucrose, mannitol), acetylsalicylic acid or clopidogrel * History of bleeding diathesis or active bleeding within the last 30 days * Recent intracerebral haemorrhage or trauma within the last 3 months * Thrombocytopenia (platelet count \<30000/mm3) at screening * Sustained hypertension (systolic BP \>179mmHg or diastolic BP \>109mmHg) at screening * Renal failure (estimated glomerular filtration rate \< 30ml/min and/or dialysis) * Severe systemic disease, such as known malignancies or other comorbid conditions with life expectancy less than one year that may result in protocol non-compliance * Unable to provide informed consent (e.g. severe dementia, or psychosis) * Current severe liver dysfunction (transaminase level \>5-fold the upper normal range limit) * Patients with an indication for anticoagulant therapy * Participation in any other clinical interventional trial (drug/device) within less than 30 days prior to screening * Any other contraindication to perform PCI * Any planned additional PCI or surgery within 30 days after randomization * Suspected poor capability to follow instructions and cooperate * Prisoners or subjects who are involuntarily incarcerated * Subjects who are compulsorily detained for treatment of either a psychiatric or physical illness (e.g. infectious disease)