Low Dose Exposure to Oxidized R-limonene - A Repeated Open Application Test (ROAT) Study

Inclusion Criteria: * Positive patch test (at least one reading) or doubtful patch test (at least two readings) to oxidized R-limonene 3% pet. (with 0.33% hydroperoxides content) according to international guidelines, within the last five years. * Aged 18 years or older * Received written and verbal information on the study. * Signed written consent form. Exclusion Criteria: * Active eczema in test areas. * Pregnancy or breast feeding. * Treatment with topical corticosteroids or other immune-suppressants on/near test areas within two weeks prior to study start. * Systemic immune-suppressant treatment within seven days prior to study start. * UV exposure of test areas within three weeks prior to study start. * Unable to cooperate or communicate with the investigators.