Evaluation of the glycemic efficacy of cabergoline on diabetic patients
Type 2 diabetes mellitus (DM) is a progressive metabolic disorder that is associated with basal hyperinsulinemia, insulin resistance and impaired insulin release. Glycemic control is a fundamental part of the management of type 2 DM and difficult to achieve. Different antidiabetic agents can handle diabetic metabolic abnormalities. The development of antidiabetic agentswith novel mechanisms of action is highly desirable. Cabergoline, a long acting D2 agonist, is expected to play a role in the glycemic control.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
60
cabergoline 0.5 mg twice weekly within 2 hrs of awakening plus gliclazide
gliclazide (60-120 mg)
Sherief Abd-Elsalam
Cairo, Egypt
RECRUITINGThe level of fasting and post prandial BG level
Fasting and post prandial BG level will be measured after 4 months
Time frame: 4 months
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