There is few randomized controlled clinical to investigated the impact of anesthetic type on outcome in patients with acute ischemic stroke in posterior cerebral circulation. It is unknown whether the choice of anesthesia is impacted on the outcomes for these patients or not. The investigators will perform a randomized controlled pilot clinical trial of general anesthesia versus local anesthesia/conscious sedation to explore and find out a potential fact whether anesthetic type alters perioperative neurological function in patients with acute ischemic stroke in posterior cerebral circulation.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
OTHER
Masking
SINGLE
Enrollment
93
Patients will be injected with propofol, remifentanil and muscular relaxant with controlled ventilation.
Patients will be injected with propofol and remifentanil.
Patients will be kept spontaneous breath.
Patient will be kept with controlled ventilation.
Ruquan Han
Fengtai, Beijing Municipality, China
Fan Wang
Guiyang, Guizhou, China
modified rankin score(mRS)
Modified rankin score(mRS)is used to evaluate the primary outcome. The scale of mRS is 0 to 6. The best neurological outcome is the mRS with 0, indicating no any symptom left, and a good neurological outcome is agreed with a mRS≤2. mRS of 6 is the worst, indicating death. mRS will be evaluated by outcomes assessor who is blinded to the grouping.
Time frame: post-procedural 90 days
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.