MEDITOXIN® in Treatment of Crow's Feet Line

Inclusion Criteria: * Male or female of at least 20 to 65 years old * Bilaterally symmetrical moderate-to-severe CFL at maximum smile on the FWS as rated by the investigator Exclusion Criteria: * Diagnosis of myasthenia gravis, Eaton-Lambert syndrome, amyotrophic lateral sclerosis * Patients with allergy or hypersensitivity to the investigational drugs or their components * Patients who have bleeding tendency or taking anti-coagulant * Female subjects who are pregnant or lactating. Female subjects of childbearing age who have a plan to get pregnant during the study period, or do not use available contraceptive methods (Women of childbearing age should have negative urine pregnancy test results at baseline visit (0 week) prior to the first injection.) * Patients who are participating in other clinical trials or have participated in other clinical trials 30 days before screening * Patients who are unable to communicate or follow the instructions * Patients who are not eligible for this study based on the judgment of an investigator