The aim of the present study is to quantify the dose and usage of sympathomimetics used in caesarean section.
Recent metaanalysis showed significantly reduced hypotension and bradycardia in patients undergoing caesarean section in spinal anesthesia when 5-hydroxytryptamine 3 receptor antagonists were used prophylactically. Due to this fact in our clinic the standard procedure was changed. All patients for caesarean section receive Granisetron before spinal anesthesia. The aim of the present study is to evaluate the usage and dose of sympathomimetics during spinal anesthesia. Therefore the investigators will evaluate approximately 120 participants who received granisetron and 120 participants who did not receive 5-hydroxytryptamine 3 receptor antagonists.
Study Type
OBSERVATIONAL
Enrollment
240
Patients received Granisetron.
Patients who did not receive Granisetron.
Klinikum Goethe Universität Frankfurt am Main
Frankfurt am Main, Hesse, Germany
Sympathomimetics
Type of sympathomimetics during during the operation
Time frame: 30 minutes starting with induction of spinal anesthesia.
Sympathomimetics
Cumulative dose of sympathomimetics during during the operation
Time frame: 30 minutes starting with induction of spinal anesthesia.
Volume substitution
Type of perioperative infused volume during the operation
Time frame: 30 minutes starting with induction of spinal anesthesia.
Volume substitution
Cumulative volume of perioperative infused volume during the operation
Time frame: 30 minutes starting with induction of spinal anesthesia.
Haemotherapy
Type of haemotherapy.
Time frame: 30 minutes starting with induction of spinal anesthesia.
Haemotherapy
Cumulative volume of haemotherapy.
Time frame: 30 minutes starting with induction of spinal anesthesia.
Duration until first application of sympathomimetics
Duration until first administration of any kind of sympathomimetics.
Time frame: 30 minutes starting with induction of spinal anesthesia.
Oxytocin
Duration until first administration of oxytocin.
Time frame: 30 minutes starting with induction of spinal anesthesia.
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Oxytocin
Cumulative dose of Oxytocin.
Time frame: 30 minutes starting with induction of spinal anesthesia.
Uterotonic agents
Kind of uterotonic agents.
Time frame: 30 minutes starting with induction of spinal anesthesia.
Uterotonic agents
Cumulative dose of uterotonic agents.
Time frame: 30 minutes starting with induction of spinal anesthesia.