The aims of the study are 1) to compare the differences in plasma coenzyme Q10, oxidative stress, antioxidant capacity, muscle impairment, fatigue recovery, and inflammation and exercise performances in athletes (i.e., soccer, and taekwondo players) and healthy non-athletes; 2) to investigate the relationship between plasma coenzyme Q10, oxidative stress, antioxidant capacity, muscle impairment, fatigue recovery, and inflammation and exercise performances; 3) to explore the influence on plasma coenzyme Q10, oxidative stress, antioxidant capacity, muscle impairment, fatigue recovery, and inflammation and exercise performances after 12 weeks of coenzyme Q10 intervention (150 mg/day and 300 mg/day).
The long-term high-amount and -intensity exercise training could cause oxidative damage, muscle impairment, inflammation and exercise fatigue to athletes easily. Such above conditions will affect the exercise performances and health of athletes. The aims of the study are 1) to compare the differences in plasma coenzyme Q10, oxidative stress, antioxidant capacity, muscle impairment, fatigue recovery, and inflammation and exercise performances in athletes (i.e., soccer, and taekwondo players) and healthy non-athletes; 2) to investigate the relationship between plasma coenzyme Q10, oxidative stress, antioxidant capacity, muscle impairment, fatigue recovery, and inflammation and exercise performances; 3) to explore the influence on plasma coenzyme Q10, oxidative stress, antioxidant capacity, muscle impairment, fatigue recovery, and inflammation and exercise performances after 12 weeks of coenzyme Q10 intervention (150 mg/day and 300 mg/day). Eventually, these results of this study can provide the information for the known to improve the oxidative stress, anti-oxidation and inflammation internal to the bodies of athletes for various competitions. As a consequence, the athletic performances can be further enhanced.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
DOUBLE
Enrollment
43
Placebo (dextrin)
150 mg or 300 mg
Chung Shan Medical University
Taichung, Taiwan
malondialdehyde (MDA)
MDA (micromol/L) will measure by thiobarbituric acid reacting substance.
Time frame: 12 weeks
Antioxidant capacity
Total antioxidant capacity (TAC) was measured by a Trolox equivalent antioxidant capacity assay in serum and erythrocytes.
Time frame: 12 weeks
high sensitivity C-reactive protein (hs-CRP)
hs-CRP will measure by immunoturbidimetry.
Time frame: 12 weeks
creatine kinase (CK)
serum CK will measure by enzymatic method.
Time frame: 12 weeks
Lactate dehydrogenase (LDH)
serum LDH will measure by enzymatic method.
Time frame: 12 weeks
one-repetition maximum (1-RM)
1RM measurements will report in kilograms for data analysis.
Time frame: 12 weeks
Glucose
mmol/L
Time frame: 12 weeks
HbA1C
HbA1C will measure by an automated glycated hemoglobin analyzer
Time frame: 12 weeks
Insulin
insulin will measure by an automated chemistry analyzer
Time frame: 12 weeks
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