Androgen Deprivation Therapy, External Beam Radiotherapy and Stereotactic Radiosurgery Boost for Prostate Cancer

Inclusion Criteria: * Pathologically confirmed intermediate- or high-risk prostate cancer within 6 months after enrollment * ECOG performance status 0-1 * Appropriate values of blood tests within 6 months after enrollment Absolute neutrophil count (ANC) ≥ 1500 cells/mm3 Platelets ≥ 50,000 cells/mm3 Hemoglobin ≥ 8.0 g/dl * Appropriate values of kidney function within 6 months after enrollment Creatinine \< 2.0 ng/dL * Appropriate values of liver function within 6 months after enrollment total bilirubin \< 1.5 X maximum normal value alanine aminotransferase or aspartate aminotransferase \< 2.5 X maximum normal value Exclusion Criteria: * Presence of distant metastasis * Presence of pelvic LN metastasis * History of androgen deprivation therapy within 6 months after enrollment * History of definitive treatment for prostate cancer (e.g., radical prostatectomy) * History of pelvic irradiation * Double primary cancer other than skin/thyroid cancer