Effect of Clomiphene Citrate on Uterine Blood Fow in Women With Unexplained Delayed Conception

Cairo University50 enrolled

Overview

In a prospective observational study at a university teaching hospital, blood flow indices and serum hormone levels were compared between spontaneous and stimulated cycles in the same group of 50 patients with unexplained delayed conception.

In a prospective observational study at a university teaching hospital, the mid-luteal (peri-implantation) endometrial thickness and volume, uterine artery pulsatility index (PI) and resistance index (RI), endometrial and subendometrial vascularization index, flow index, and vascularization flow index, and serum estradiol and progesterone levels were compared between spontaneous and clomiphene citrate stimulated cycles in the same group of 50 patients with unexplained infertility.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Infertility, Female

Interventions

Vascularization indices observationOTHER

The mid-luteal endometrial thickness and volume, uterine vascularization indices of uterine artery pulsatility index and resistance index, endometrial and subendometrial vascularization index, flow index, and vascularization flow index, and serum estradiol and progesterone levels were calculated in spontaneous then stimulated cycles in the same group of infertile patients

Eligibility

Sex: FEMALEMin age: 25 YearsMax age: 35 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Unexplained infertility * Body mass index less than 30 * Regular menstruation * Normal pelvic examination and ultrasonography Exclusion Criteria: * History of pelvic operations including cesarean section * History of pelvic inflammatory disease * Endometriosis * Pelvic pathology including uterine fibroids * General disease or medication that could potentially affect pelvic blood flow * Smoking

Locations (1)

Department of Obstetrics and Gynecology, Kasr Al-Ainy hospital, Cairo University

Cairo, Greater Cairo, Egypt