The Comparison About the Response of Ursodeoxycholic Acid in Primary Biliary Cholangitis Only and Primary Biliary Cholangitis With High Immune Globulin G or Aminotransferase at West China Hospital

West China Hospital300 enrolled

Overview

This study evaluates the different response of Ursodeoxycholic Acid in primary biliary cholangitis only and primary biliary cholangitis with high immune globulin G or aminotransferase at West China Hospital from 2008-2017.

Study Type

OBSERVATIONAL

Enrollment

300

Conditions

Primary Biliary Cholangitis

Eligibility

Sex: ALLMin age: 25 YearsMax age: 85 Years

Medical Language ↔ Plain English

Inclusion Criteria: Patients diagnosed with primary biliary cholangitis Treated with Ursodeoxycholic Acid in West China Hospital for at least 1 year Exclusion Criteria: Autoimmune hepatitis Primary sclerosing cholangitis

Locations (1)

West China Hospital

Chengdu, Sichuan, China

Outcomes

Primary Outcomes

Description of demographics, clinical index after treatment

age，sex，ALT（IU/L），AST（IU/L），ALP（IU/L），GGT（IU/L）,IgG（g/L）

Time frame: up to 1 year

Secondary Outcomes

Evaluation whether the PBC patients have response after treatment

Use Paris II criterion to estimate

Time frame: within 1 year

Data from ClinicalTrials.gov

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