Preemptive Analgesia for Primary Dysmenorrhoea

Hanan Nabil84 enrolled

Overview

Preemptive analgesia before the release of pain mediators

spasmodic dysmenorrhea is one of the most distressing symptoms in women. adolescents shows a usual absence from school . prostaglandin release is one of the most accepted theory responsible for spasmodic dysmenorrhea. Non steroidal anti inflammatory Drugs were proved to be one of the alternative medications for spasmodic dysmenorrhea. Getting the idea of what is called preemptive anesthesia by blocking the receptors before catching pain mediators the study participants will be divided randomly into 2 group group 1 receiving ttt 2 days before the anticipated menstruation and group 2 receiving ttt only during menstruation as analgesia

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

SUPPORTIVE_CARE

Masking

NONE

Enrollment

Conditions

Primary Dysmenorrhea

Interventions

preemptive mefenamic acidDRUG

preemptive analgesia before menstrual pain

mefenamic acidDRUG

mefenamic acid given only during menstruation

Eligibility

Sex: FEMALEMin age: 15 YearsMax age: 25 Years

Medical Language ↔ Plain English

Inclusion Criteria: * nulliparous ladies * with regular menstrual cycle pattern * those experienced history of dysmenorrhea (primary or spasmodic) * patients able to sallow tables Exclusion Criteria: * irregular cycles * any associated local causes( pelvic infection, endometriosis, fibroid or others) * patients with familial Mediterranean fever or other intermenstrual attacks of abdominal pain * gastric or duodenal ulcers or gastritis * other contraindications to non steroidal anti-inflammatory drugs * patients with severe diminution of vision or color discrimination * patients with any depressive or mood disorders * patients receiving any hormonal treatment

Locations (1)

Mansoura University

Al Mansurah, Egypt

Outcomes

Primary Outcomes

change in the Degree of pain

severity of pain according to visual pain analog scale

Time frame: 4 months

Data from ClinicalTrials.gov

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