Fitness, Physical Activity and Movement Analysis in Obese Patients Undergoing Bariatric Surgery

Assistance Publique - Hôpitaux de Paris27 enrolled

Overview

This study aims to describe the effects of sleeve gastrectomy, the most commonly performed bariatric procedure worldwide, on functional capacity, habitual physical activity, physical fitness (cardiorespiratory and muscular fitness) and gait parameters in severely obese subjects undergoing bariatric surgery. Functional capacity, physical activity, physical fitness and gait parameters will be objectively assessed and compared among candidates seeking sleeve gastrectomy and 6 months after sleeve gastrectomy.

This study is a monocentric longitudinal study conducting in obese patients: candidates to sleeve gastrectomy and these same patients 6 months after.The primary aim of this study is to describe the effects of sleeve gastrectomy on habitual physical activity, physical fitness (cardiorespiratory and muscular fitness) and gait parameters in severely obese patients. Functional capacity will be assessed during a 6-min walk test, habitual physical activity with accelerometers during 7-day recordings in habitual life conditions (Actigraph GT3X® and activPAL®), cardiorespiratory fitness during a maximal exercise test on a cycle ergometer with a direct measure of peakVO2, muscle strength with an isokinetic dynamometer (Contrex®), muscle power and postural stability with force platforms (Kistler® and Satel®) and gait parameters with a gait analysis system (GaitRite®). Fatigue, quality of life and joint pain will be assessed with questionnaires (MFI-20, SF36 and WOMAC, respectively).

Study Type

INTERVENTIONAL

Allocation

Purpose

OTHER

Masking

NONE

Enrollment

Conditions

Sleeve Gastrectomy

Interventions

functional assessmentOTHER

assessment of functional capacity, habitual physical, cardiorespiratory fitness, muscle power and postural stability and gait parameters

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Female gender * Age between 18 and 65 years * Planned obesity treatment by sleeve gastrectomy * Patient with massive obesity (BMI ≥ 40 kg/m2) or severe obesity (BMI between 35 and 40 kg/m2) with comorbidities * Written informed consent Exclusion Criteria: * Subject not affiliated with a social security scheme * Regular follow-up not feasible * Participation in a structured physical activity program * Severe orthopedic problems * Disabling neuropathy * Recent (\< 6 months) coronary event * Abnormal cardiac stress test * Pregnancy

Locations (1)

GH-Pitié-Salpêtrière

Paris, France

Outcomes

Primary Outcomes

functional capacity

Difference in functional capacity (6-min walk test distance)

Time frame: before and 6 months after sleeve gastrectomy

Secondary Outcomes

habitual physical activity (Actigraph GT3X® and activPAL®)

Difference in habitual physical activity

Time frame: before and 6 months after sleeve gastrectomy

cardiorespiratory fitness ( cycle ergometer )

Difference in cardiorespiratory fitness

Time frame: before and 6 months after sleeve gastrectomy

muscle strength ( isokinetic dynamometer (Contrex®))

Difference in muscle strength

Time frame: before and 6 months after sleeve gastrectomy

Data from ClinicalTrials.gov

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