This study evaluates the effectiveness of Guttmann NeuroPersonalTrainer (GNPT), a tele-rehabilitation platform developed as a tool for the cognitive rehabilitation of chronic stroke patients. All patients will receive this treatment but in different order: half will receive GNPT and the other half will receive sham cognitive training; after a washout period of three months, crossover will occur and participants from the GNPT condition will receive sham cognitive training, while participants originally from the control intervention will receive GNPT.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
41
Guttmann NeuroPersonalTrainer (GNPT) is a telerehabilitation platform. GNPT consists of a set of computerized cognitive exercises covering different cognitive functions and subfunctions. Every task has been specifically based on cognitive paradigms to address specific cognitive subfunction. The rehabilitation process starts by assigning a patient to a therapist responsible for the treatment. The therapist has then to perform the initial neuropsychological assessment, consisting of a set of validated tests used to attention, memory and executive functions prior to the treatment. The results of these tests will be stored in GNPT system. Then, the cognitive profile is calculated using these results, and taking into account the patient's age and study level. Using this profile, the program assigns a set of computerized tasks to a certain day, configuring the input parameters of each task in order to personalize treatments.
An online domain which provides a daily session of one hour of duration. Each session consists of four ten-minute videos. After each video, the participant must complete a three-question quiz about the contents of the video (for example, "What animal appears in in the video?"). The difficulty level is minimal, and does not vary depending on the execution of the participant.
Institut Guttmann
Barcelona, Spain
Conners Continuous Performance Test (CPT-II)
To improve performance in sustained attention after receiving experimental intervention.
Time frame: 1 day
Rey Auditory Verbal Learning Test (RAVLT)
To improve performance in short-term, long-term and recognition. This test has puntuation range from 0 to 75.
Time frame: 1 day
Spanish phonemic fluency test- PMR
To improve performance in phonemic fluency after receiving experimental intervention.
Time frame: 1 day
Digit Span forward Subtest from the Wechsler Adult Intelligence Scale (WAIS-III)
To improve performance in span of immediate verbal recall after receiving experimental intervention. This subtest has a puntuation range from 2 to 9, where higher values are considered to be a better outcome.
Time frame: 1 day
Digit Span backward Subtest from the Wechsler Adult Intelligence Scale (WAIS-III)
To improve performance in working memory after receiving experimental intervention. This subtest has a puntuation range from 2 to 8, where higher values are considered to be a better outcome.
Time frame: 1 day
Letter-Number Sequencing Subtest from the Wechsler Adult Intelligence Scale (WAIS-III)
To improve performance in working memory after receiving experimental intervention. This subtest has a puntation range from 1 to 21, where higher values are considered to be a better outcome.
Time frame: 1 day
Rating Scale for Attentional Behavior (RSAB)
RSAB comprises 14 items aimed to identify attentional difficulties on daily routines
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Time frame: 1 week
Prospective and Retrospective Memory Questionnaire (PRMQ)
PRMQ includes 16 items designed to evaluate prospective and retrospective memory in short- and long-term
Time frame: 1 week
Behavior Rating Inventory of Executive Function-Adult Version (BRIEF-A)
BRIEF-A includes 75 items designed to assess executive function behaviors on day-to-day activities.
Time frame: 1 week
Digit Symbol-Coding Subtest from the Wechsler Adult Intelligence Scale (WAIS-III)
To improve performance in speed of processing. This subtest has a puntuation range from 1 to 133, where higher values are considered to be a better outcome.
Time frame: 1 day
Block Design Subtest from the Wechsler Adult Intelligence Scale (WAIS-III)
To improve performance in visuoconstruction and planning. This subtest has a puntuation range from 1 to 68, where higher values are considered to be a better outcome.
Time frame: 1 day
Stroop Color and Word test (Stroop Test)
To improve performance in inhibitory control
Time frame: 1 day
Trail Making Test A (TMT-A)
To improve performance in visual attention
Time frame: 1 day
Trail Making Test B (TMT-B)
To improve performance in task-switching
Time frame: 1 day
Wisconsin Card Sorting Test (WCST)
To improve performance in cognitive flexibility
Time frame: 1day