Study design. The study FRAGIREA is a multicentric prevalence study on the frequency of frailty among elderly patients and the quality of management. The voluntary ICUs will have to include all patients ≥ 70 years on a limited period (1 month) or until the number of 15 inclusions is reached. The frailty is going to be evaluated by a frailty score adapted to the ICU, based on informations given by the patient's family. It is a descriptive non-interventional study, aiming at the description of frequency of frailty and management of the patient in order to set-up a prospective future study on the potential role of early rehabilitation of ageing patients in ICUs.
Study Type
OBSERVATIONAL
Enrollment
527
Determine the prevalence of frailty in elderly patients (≥ 70 year old) in a group of French ICUs. The frailty is measured by a score (Fried score) at the admission of the patient
CH Aix en Provence
Aix-en-Provence, France
CHU Angers
Angers, France
CH Annecy
Annecy, France
CH Annonay
Annonay, France
CH Argentueil
Argenteuil, France
CH Belfort
Belfort, France
CH Béziers
Béziers, France
CH Bourg en Bresse
Bourg-en-Bresse, France
CH Bourgoin-Jallieu
Bourgoin, France
CH Chalons sur Saône
Chalon-sur-Saône, France
...and 27 more locations
Frailty in elderly (≥70 years old) patients in intensive care unit (ICU)
We assessed the 5 components of Fried's frailty index, resulting from cumulative decline across multiple physiological systems and contain five criteria (shrinking, weakness, slowness, low-level physical activity, and self-reported exhaustion). All five components were considered from the previously reported definition and adapted to the ICU environment. The patients were considered to be frail if they had three or more frailty components among the five criteria.
Time frame: One month or 15 patients ≥ 70 years old
Organ failures
During the patients' hospitalization in ICU, the following data were collected last day in ICU: the need for dialysis during ICU the duration of mechanical ventilation (number of days under mechanical ventilation) the duration of shock (number of days under catecholamines)
Time frame: About 8 days
Nutritional support
Nutritional intake during ICU stay, from the first day to the patient's exit, including route of administration (enteral, parenteral), last day in ICU we assessed: number of days under enteral nutrition number of days under enteral parenteral nutrition calculation of the average calorie / day
Time frame: About 8 days
Rehabilitation
Last day in ICU, we record the highest level of mobilization achieved during the ICU period, the following ordinal scale was used: 1) no mobilization, 2) turning in bed, 3) sitting in bed with the head of bed elevated, 4) sitting on the edge of the bed with feet on floor, 5) sitting out of bed in a chair, 6) standing out of bed, 7) marching in place, 8) walking, 9) using cycloergometer and 9) using electrical muscle stimulation.
Time frame: About 8 days
Mortality
ICU mortality and Hospital mortality Decision of therapeutics limitation. Length of stay (ICU and hospital stay).
Time frame: 90 days
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