Background \& Purpose: Cervical radiculopathy is a neurological disorder, which commonly results because of nerve compression. There are different types of physical therapy interventions that are used for cervical radiculopathy. The evidence of effectiveness of manual therapy in cervical radiculopathy is still limited. Short-term hypoalgesic effects after manual therapy was found in different musculoskeletal conditions. However, the effectiveness of manual therapy in patients with cervical radiculopathy hasn't been investigated yet. Therefore, the aim of study is to examine the short-term effect of manual therapy (mobilization) on the sensory features in patients with chronic cervical radiculopathy.
Participants: The sample size was calculated using G\*power 3.1(F test, analysis of variance \[ANOVA\]: repeated measure, within between interaction, and a priori: compute required sample size). A result of 10 participants (treatment group=5 and sham group=5) was used to calculate the effect size (ES) of 0.44 for the pressure pain threshold on the cervical spine after the intervention(immediate effect) between group. The power estimated for ANOVA for the two group with a significance of 0.05 revealed that a total sample size of 28 participants was necessary to obtain a power of 0.80. . a minimum of 14 needed to be recruited in this study Participants with unilateral neck pain and radiating symptoms to upper extremity of more than three months were recruited from King Abdul-Aziz Hospital and East Jeddah general hospital in Jeddah, Saudia Arabia All patients signed a consent form before they participate in the study after explaining all procedures to them. The study was approved by the Institutional Review Board (IRB) at the University of Dammam (IRB Number: PGS-20160-30-142) and was approved by ministry of health at Saudia Arabia (IRB number: H-02J-002). All electronic data pertinent to the patients were being saved in a secured laptop, whereas the paper document will be kept in a locked cabinet. Data analysis: All statistical analysis was performed using IBM SPSS version 20 (Armonk, NY: IBM Corp). Significance levels will be set at p ≤ 0.05. Mean and standard deviation will be calculated as descriptive statistics. One-way repeated measures analysis of variance (ANOVA) and post hoc comparison, if needed will calculate the differences in the outcome measures: Quantitive sensory testing (QST), pain intensity, and active CROM
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
28
1. Manual therapy: One of the following techniques was used for the treatment group based on the patients' response (i.e centralization and reduction of symptoms). 1. Cervical postero-anterior vertebral mobilization glides: a central posteranterior (PA) or unilateral PA oscillatory pressure of grade III on the patient's most symptomatic level for 2 minute and 3 sets . 2. Cervical lateral vertebral glides :at grade III for 1 minute and 3 sets. 2. Strengthening Exercises: for deep neck flexor muscles for 10 seconds and repeating it for 10 times.
1\. Superficial soft tissue massage: The researcher applied a superficial effleurage massage without moving the deeper tissue for 2 minutes for 3 sets Strengthening Exercises: for deep neck flexor muscles for 10 seconds and repeating it for 10 times
East jeddah general hospital
Jeddah, Saudi Arabia
king Abdulaziz hospital
Jeddah, Saudi Arabia
pressure pain threshold (PPT)
An electronic algometer (Somedic AB, Farsta, Sweden) was used to quantify pain intensity (K pascal).
Time frame: Change from baseline in PPT at immediate post intervention
pressure pain threshold (PPT)
An electronic algometer (Somedic AB, Farsta, Sweden) was used to quantify pain intensity (K pascal).
Time frame: Change from baseline in PPT at 3 weeks post intervention
Warmth/cold detection threshold and heat/cold pain threshold
A Thermotest System (SenseLab - Modular Sensory Analyser, Somedic AB, Horby, Sweden) was used to determine the thermal thresholds in degrees (°C )
Time frame: Change from baseline in thermal detection & pain threshold at immediate post intervention
Warmth/cold detection threshold and heat/cold pain threshold
A Thermotest System (SenseLab - Modular Sensory Analyser, Somedic AB, Horby, Sweden) was used to determine the thermal thresholds in degrees (°C )
Time frame: Change from baseline in thermal detection & pain threshold at 3 weeks post intervention
The Neck Disability Index (NDI)
The NDI is used to measure the patient reported disability in percentage
Time frame: Change from baseline in NDI at immediate post intervention
The Neck Disability Index (NDI)
The NDI is used to measure the patient reported disability in percentage
Time frame: Change from baseline in NDI at 3 weeks post intervention
Active Cervical Range of Motion
Cervical range of motion (CROM) device was used to assess the cervical range of motion in degree.
Time frame: Change from baseline in CROM at immediate post intervention
Active Cervical Range of Motion
Cervical range of motion (CROM) device was used to assess the cervical range of motion in degree.
Time frame: Change from baseline in CROM at 3 weeks post intervention
Numerical Pain Rating Scale (NPRS)
The NPRS was used to assess a patient's level of pain in (11 points: 0 means no pain and 10 means severe pain.
Time frame: Change from baseline in NPRS at immediate post intervention
Numerical Pain Rating Scale (NPRS)
The NPRS was used to assess a patient's level of pain in (11 points: 0 means no pain and 10 means severe pain.
Time frame: Change from baseline in NPRS at 3 weeks post intervention
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.