Effect of Epidural Anesthesia on Blood Flow in Arterial Anastomosis of Free Flap

Asan Medical Center52 enrolled

Overview

Comparing the changes of arterial anastomotic blood flow between general anesthesia alone and general anesthesia with epidural anesthesia in patients who undergoing free flap transposition using Duplex ultrasound.

Maintaining adequate blood flow is important on the success of free flap surgery. Epidural anesthesia can influence blood flow during surgery. Therefore, investigators aim to compare the effect of epidural anesthesia combined with general anesthesia and general anesthesia alone on blood flow in arterial anastomosis site of the free flap.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

OTHER

Masking

QUADRUPLE

Enrollment

Conditions

Free Tissue Flaps

Interventions

Epidural anesthesiaOTHER

After anesthesia induction, epidural catheter is inserted into lumbar epidural in epidural with general anesthesia group. A 10 ml of 0.2% ropivacaine should be given in epidural space via a catheter when anastomosis of free flap is finished in epidural with general anesthesia group.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 79 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients scheduled to undergo free flap transfer under general anesthesia. * 18 years of age or older, under 80 years of age * Those who voluntarily agreed to participate in this clinical study Exclusion Criteria: * If the patient does not agree to participate in the study * ASA physical status IV or higher * If the patient was diagnosed with diabetes * If the patient was diagnosed with chronic renal failure * If the patient was diagnosed with peripheral vascular disease or hyperlipidemia * If vasopressors or inotropics was used preoperatively. * Contraindication of epidural anesthesia such as usage of anticoagulant or abnormalities of laboratory finding. * If the researcher finds it to be inappropriate

Locations (1)

Asan Medical Center

Seoul, South Korea