This study is examining the effects of the 2940 nm Er:YAG on atrophic facial acne scars under optical coherence tomography in terms of blood flow, vessel shape, skin roughness, collagen content, and epidermal thickness.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
The Erbium YAG laser at a 2940nm wavelength is used for ablative laser resurfacing as well as treating acne scars.
Sylvester Comprehensive Cancer Center
Miami, Florida, United States
Change in blood flow
Optical coherence tomography (OCT) will be used to quantitatively measure changes in facial atrophic acne scars in terms of blood flow (proportion of signals with strong dynamic signal (%)/depth (mm)).
Time frame: During 8 weeks
Change in epidermal thickness
Optical coherence tomography (OCT) will be used to quantitatively measure changes in facial atrophic acne scars in terms of epidermal thickness (mm).
Time frame: During 8 weeks
Change in collagen content
OCT will be used to qualitatively measure changes in facial atrophic acne scars in terms of collagen content. Collagen content will be measured in terms of brightness of OCT scan. Areas of skin that contain collagen tend to be brighter (more white in color) whereas areas with less collagen content tend to be darker.
Time frame: During 8 weeks
Change in skin roughness
OCT will be used to quantitatively measure changes in facial atrophic acne scars in terms of skin roughness (µm).
Time frame: During 8 weeks
The Patient Scar Assessment Scale
Scale (1-10) used to qualitatively monitor treatment and changes in scars by the patient.
Time frame: During 8 weeks
The Observer Scar Assessment Scale
Scale (1-10) used to qualitatively monitor treatment and changes in scars by the dermatologist.
Time frame: During 8 weeks
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