2 Arms (60 subjects - 30 each arm). Experimental group with two-pice zirconia dental implant and Control group with two-piece titanium dental implant Evaluate Changes in inflammatory and microbiology levels from T0 (baseline) T2 (8 weeks) and T3 (after crown placement) Also evaluate secondary outcomes: marginal bone loss (MBL), gingival height (GH) levels, osseointegration, gender, age, time of surgery, anatomical position and implant stability. p values\<0.05 were considered statistically significant
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
60
Place a two piece zirconia dental implant on a healed ridge. At baseline, two month and crown placement take fluid samples with adsorbent paper in the per- implant crevicular fluid. At t2 and t3 repeat sample taken
Osseointegration
measure if the healing process of bone was successful
Time frame: from T0 to T2 - 2 month
Marginal bone loss
measure bone level from T0 baseline to T3
Time frame: 4 month after T0
IL1b concentration
Measure IL fluid at T0 and T2 for IL1b characterization
Time frame: 4 month
IL6 concentration
Measure IL fluid at T0 and T2 for IL1b characterization
Time frame: 4 month
Microbiologic samples
Measure crevicular fluid at T0 and T2 for bacteria characterization
Time frame: 4 month
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