Evaluation of Long-term Coronary Stenting Outcomes in Diabetic Patients With or Without Optimal Glycemic Control

Tehran Heart Center1,353 enrolled

Overview

the purpose of this study is to determine whether appropriate control of diabetes around the PCI time is related with MACE and outcome of diabetic patients.

Despite recent advances in coronary revascularization, cardiovascular disease accounts for about 75% of all hospital admissions in diabetic patients.although the introduction of drug-eluting stents has reduced the rates of restenosis after PCI, diabetic patients undergoing PCI will have poorer clinical outcomes.In this study, we sought to investigate whether a pre and post procedural glycemic control in diabetic patients,as reflected by HgbA1C prior,1 and 6 months after elective PCI,was related to major advance cardiac events (MACE) during 3 year follow up.

Study Type

OBSERVATIONAL

Enrollment

1,353

Conditions

Diabetes Coronary Artery Disease

Eligibility

Sex: ALLMin age: 18 YearsMax age: 75 Years

Medical Language ↔ Plain English

Inclusion Criteria: * age between 18-75 * coronary stenosis \> 70% Exclusion Criteria: * Myocardial infarction in 72 hours prior to PCI * LVEF \< 30% * Residual Stenosis\>30% * Cr level \> 2.0 * hemodynamic compromise during intervention * Left main lesions * PCI for vein grafts

Locations (1)

Tehran heart center, Tehran university of medical sciences

Tehran, Iran

Outcomes

Primary Outcomes

Major adverse cardiac event

Time frame: during 3 years after per-cutaneous coronary intervention

Secondary Outcomes

target vessel revascularization

Time frame: during 3 years after PCI

target lesion revascularization

Time frame: during 3 years after PCI

Data from ClinicalTrials.gov

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