The purpose of this study was to investigate the serum concentrations, physical and psychological well-being characteristics in patients having chronic musculoskeletal pain with metabolic syndrome, and to compare patients without metabolic syndrome.
Metabolic syndrome (MetS) is a combination of metabolic risk factors such as impaired glucose level, dyslipidemia, hypertension, and central obesity. MetS has become a large public health issue with common interrelation to different accompanying disorders. Moreover, the link between MetS and musculoskeletal disorders has previously been demonstrated. Presence and prevalence of MetS in patients having musculoskeletal pain seems common and interrelated.However, to our knowledge, manifestations with clinical symptoms of MetS, some inflammatory markers via serum concentrations and physical and psychological health profiles of patients with seeking treatment from outpatient physical therapy for musculoskeletal pain conditions have not been researched up to now.
Study Type
OBSERVATIONAL
Enrollment
100
evaluated by Bodystat®1500 Bio-impedance Analyzer
assessed by the International Physical Activity Questionnaire-7
evaluated with Visual Analog Scale
Ataturk Training and Research Hospital
Ankara, Cankaya, Turkey (Türkiye)
ACTIVE_NOT_RECRUITINGAtaturk Training and Research Hospital
Ankara, Cankaya, Turkey (Türkiye)
RECRUITINGBlood tests
for uric acid levels.
Time frame: 2 years
Body composition
evaluated by Bodystat®1500 Bio-impedance Analyzer
Time frame: 2 years
Physical activity level
assessed by the International Physical Activity Questionnaire-7. The intensity of self-reported physical activity, lasting at ten minutes per bout, was used to assess metabolic equivalent (MET). The MET is defined as the ratio of a working metabolic rate to a standard resting metabolic rate.MET-minutes/week was computed by multiplying the MET score of an activity (3.3 for walking, 4.0 for moderate-intensity, and 8.0 for vigorous-intensity) by the minutes and days performed. The summation of walking, moderate, and vigorous METs-minutes/week enabled the computation of the total physical activity performed by an individual.
Time frame: 2 years
The musculoskeletal pain intensity
evaluated with 0 to 10 cm Visual Analog Scale. "0" indicated "no pain" and the "10" indicated "the worst imaginable pain".
Time frame: 2 years
Quality of life
evaluated with the Nottingham Health Profile (NHP). It contains 38 items divided into 6 dimensions: NHP-energy, NHP-pain, NHP-emotional reactions, NHP sleep, NHP-social isolation, and NHP-physical mobility. All the parameters are summed as NHP-total. The respondent answers "yes" if the statement adequately reflected the current status or feeling, or "no" otherwise. Dimension scores ranged from 0 (no problems) to 100 (maximum problems).
Time frame: 2 years
Psychological Well-Being (Anxiety and Deppression condition)
evaluated with the Hospital Anxiety and Depression Scale (HADS). Each question was scored on a 4-point Likert scale, ranging from 0 to 3, where a higher score represented more severe anxiety or depression.
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assessed by the Nottingham Health Profile
assessed by the Hospital Anxiety and Depression Scale
Blood tests included serum glucose, triglyceride, high-density lipoprotein cholesterol (HDL-C), and uric acid levels. Blood samples were collected from the patients after one night of fasting.
Time frame: 2 years