This study investigate the prevalence of elevated biomarkers of cardiac injury in patients with suspected influenza infection and the prognostic implication on the composite endpoint of death of any cause, hospitalization due to myocardial infarction, unstable angina, heart failure and stroke.
The relationship between influenza and cardiovascular events was described in an early study of influenza epidemics from 1915 to 1929 including the 1918-1920 pandemic. Retrospective studies have shown increased risk for acute myocardial infarction (AMI) during the first week following an infection with influenza. Biochemical markers of cardiac injury such as high sensitive cardiac troponins may be increased during infection with influenza. Increased levels of cardiac troponins are associated with adverse outcome in many different populations.
Study Type
OBSERVATIONAL
Enrollment
466
Örebro University
Örebro, Sweden
Level of biochemical markers
Level of cardiac troponin in patients with influenza The level of hs-cTn, NT-proBNP and hs-CRP at inclusion in patients with and patientes without influenza.
Time frame: One year
Level of biochemical markers
Level of other biochemical markers in patients with influenza
Time frame: One year
Prognostic implication
Time to all-cause death
Time frame: One year
Prognostic implication
Time to admission for myocardial infarction
Time frame: One year
Prognostic implication
Time to admission for unstable angina
Time frame: One year
Prognostic implication
Time to admission for heart failure
Time frame: One year
Prognostic implication
Time to admission for stroke
Time frame: One year
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