NCT03344432 - Correlation Intraocular Pressure With Intracranial Pressure | Crick

Overview

Severe Trauma Brain Injury (TBIs) is a public health problem and monitoring of Intracranial Pressure (ICP) is a determinant key of it prognosis. Within the noninvasive methods to estimate the ICP, the measurement of intraocular pressure has been proposed because of its biological plausibility (proximity of the eye to the encephalic contend). Objective. Correlate intraocular pressure with ICP in children with TBIs and obtain their utility values.

Severe Trauma Brain Injury (TBIs) is a public health problem and monitoring of Intracranial Pressure (ICP) is a determinant key of it prognosis. Within the noninvasive methods to estimate the ICP, the measurement of intraocular pressure has been proposed because of its biological plausibility (proximity of the eye to the encephalic contend). Objective. Correlate intraocular pressure with ICP in children with TBIs and obtain their utility values. Material and methods. Correlation and diagnostic test design study. Inclusion criteria: children with TBIs admitted to the emergency room and indication of catheter for ICP measurement. Exclusion criteria: injury or ophthalmic disease, glaucoma, encephalic death. Intraocular pressure was measured with electronic tonometer in both eyes prior to placement of the catheter for ICP measurement. Correlation was estimated with Spearman's Rho. The utility values of the diagnostic test were obtained from an Receiver Operating Characteristic curve.

Study Type

OBSERVATIONAL

Enrollment

30

Conditions

Intraocular Pressure Intracranial Pressure Increase Trauma, Brain Children, Only

Interventions

with intraocular pressure highDIAGNOSTIC_TEST

Measurement of intraocular pressure The measurement will be made with a electronic minimum contact tonometer for measuring intraocular pressure immediately before the placement of the invasive catheter for measurement of intracranial pressure.

without intraocular pressure highDIAGNOSTIC_TEST

Measurement of intraocular pressure The measurement will be made with a electronic minimum contact tonometer for measuring intraocular pressure immediately before the placement of the invasive catheter for measurement of intracranial pressure.

Eligibility

Sex: ALLMin age: 2 YearsMax age: 15 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. Children with severe trauma brain injury (Coma Glasgow Scale smaller than 9 points), 2. who have been admitted to the pediatric emergency room 3. and in whom the treating neurosurgeon has decided to place a catheter for intracranial pressure measurement. Exclusion Criteria: 1. Ocular trauma, 2. brain death, 3. know eye disease, 4. refusal of parents or guardians to participate in the study.

Locations (1)

Hospital Civil Fray Antonio Alcalde

Guadalajara, Jalisco, Mexico

RECRUITING

Outcomes

Primary Outcomes

Intraocular pressure smaller than 20 mmHg

Abscence of increased intraocular pressure (smaller than 20 mmHg) without intracranial pressure smaller than 20 mmHg.

Time frame: Immediately

Secondary Outcomes

Intraocular pressure equal or more than 20 mmHg

Intraocular pressure equal or more than 20 mmHg with Intracranial pressure equal or more than 20 mmHg

Time frame: Immediately

Central Contacts

Karla Isis I Aviles-Martinez, PhD

CONTACT

39424400 draisispediatra@yahoo.com.mx

Adriana López-Enríquez, MD

CONTACT

39424400 aleurg2@hotmail.com