MRI of Sacroiliac Joints: Evaluation of Accuracy of Dixon Sequences in the Diagnosis of Axial Spondyloarthritis

Centre Hospitalier Universitaire de Nīmes5 enrolled

Overview

The investigators hypothesize that the T1 Dixon post-Gadolinium and T2 Dixon sequences will show good diagnostic performances for active sacroiliitis compared to the reference test (Short tau inversion recovery) and clinical-biological criteria, which will allow a better diagnosis of active sacroiliitis

Study Type

OBSERVATIONAL

Enrollment

Conditions

Spondyloarthritis

Interventions

ImagingDIAGNOSTIC_TEST

Coronal oblique T1, Coronal oblique and axial STIR, Coronal oblique T1 Dixon, Coronal oblique and Axial T2 Dixon and T1 Dixon post Gadolinium

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * The patient must have given their free and informed consent and signed the consent form * The patient must be a member or beneficiary of a health insurance plan * The patient is at least 18 years old * The patient has a clinically diagnosed axial spondyloarthritis (axSpA) (ASAS or AMOR classification) * Patient has an active axSpA (BASDAI\>4) Exclusion Criteria: * The subject is participating in another study, or is in a period of exclusion determined by a previous study * The subject refuses to sign the consent * It is impossible to give the subject informed information * The patient is under safeguard of justice or state guardianship * The patient is pregnant or breastfeeding * The patient has a contra-indication

Locations (2)

CHU Lapeyronie

Montpellier, France

CHU Nimes

Nîmes, France

Outcomes

Primary Outcomes

Diagnostic performance of T1 Dixon post-Gadolinium and T2 Dixon for active sacroiliitis, according to subchondral edema status

compared to ASAS criteria incorporating Short tau inversion recovery and clinic-biological elements

Time frame: Time 0

Secondary Outcomes

Diagnosis of enthesitis from T1 Gadolinium Dixon sequence vs ASAS criteria

Yes/no

Time frame: Time 0

Diagnosis of synovitis from T2 Dixon and T1 Gadolinium Dixon sequences vs ASAS criteria

Yes/no

Time frame: Time 0

Diagnosis of chronic sacroiliite (erosion or chondral scler osis, or fatty spinal replacement) by T1 Dixon pre-Gadolinium

Yes/No

Time frame: Time 0

Diagnosis of chronic sacroiliite (erosion or chondral sclerosis, or fatty spinal replacement) by conventional sequences

Yes/no

Time frame: Time 0

Data from ClinicalTrials.gov

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