Autonomic Dysfunction in Patients With Pectus Excavatum.

Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation120 enrolled

Overview

Investigators conducted a pilot study to to evaluate the autonomic function in participants with pectus excavatum before and after Nuss surgery.

Since pectus excavatum can cause cardiac arrhythmia, the cardiac autonomic function in participants with pectus excavatum might be impaired. However, to our knowledge, there is no any study to evaluate the cardiac autonomic function in participants with pectus excavatum.

Study Type

OBSERVATIONAL

Enrollment

120

Conditions

Pectus Excavatum Autonomic Dysfunction Surgery

Interventions

Nuss surgeryPROCEDURE

surgical correction for pectus excacatum

Eligibility

Sex: ALLMin age: 13 YearsMax age: 45 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: 1. Clinical diagnosis of pectus excavatum 2. Agree to receive Nuss surgery to correct pectus excavatum Exclusion criteria: 1. Major medical disease (asthma, heart failure, renal disease) 2. Known psychiatric disease 3. Known sleep-disordered breathing 4. Skeletal disease 5. Major surgery within 6 months

Locations (1)

Taipei Tzu-Chi Hospital, Buddhist Tzu-Chi Medical Foundation

New Taipei City, Taiwan

RECRUITING

Outcomes

Primary Outcomes

The impact of Nuss surgery on HRV in patients with pectus excavatum

If Nuss surgery can improve HRV in different stress in patients with pectus excavatum?

Time frame: 6 months

Central Contacts

Mei-Chen Yang, MD

CONTACT

+886-66289779 mimimai3461@gmail.com

Data from ClinicalTrials.gov

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