Evaluation of DEX-IN During Outpatient Procedures

Inclusion Criteria: * Voluntarily provide written informed consent * Be planned to undergo a selected office-based or outpatient procedure * Be naïve to the planned procedure, i.e. no repeated or revision procedures * Not pregnant or planning to become pregnant, or using appropriate contraceptive measures. Exclusion Criteria: * Known allergy to any study treatment or excipient * Have another painful physical condition or anxiety related diagnosis that may confound study assessments * Evidence of a clinically significant finding on physical examination, laboratory assessment, or ECG * Have signs or a history of significant nasal condition that may interfere with intranasal drug delivery