Efficacy Evaluation of the Probiotics Containing Skincare Products on Skin

GenMont Biotech Incorporation20 enrolled

Overview

Previous studies on skin health with Lactic acid bacteria (LAB) have been published for many years, including prevention of skin diseases and improvement of skin conditions. In this clinical study, the investigators researched the benefit effects of heat-killed Lactobacillus plantarum cream on skin health.

To evaluate the efficacy of applying probiotic cream in the ameliorationof the whole face skin conditions such as moisturizing, whitening, anti-wrinkle and so on.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

SUPPORTIVE_CARE

Masking

NONE

Enrollment

Conditions

Skin Problems

Interventions

Emulsion base with probioticsCOMBINATION_PRODUCT

Water、Polyglyceryl-3/ Methylglucose Distearate、Triethyl Hexanoin、Macadamia Ternifolia Seed Oil、Propanediol、PEG/PPG/Polybutylene Glycol-8/5/3 Glycerin、Cetyl Alcohol、Myristyl Myristate、Glycerin、Glycosyl Trehalose/Hydrogenated Starch Hydrolysate、Rice Ferment Filtrate(Sake)、Saccharomyces/Daylily Flower Ferment Filtrate、Bis-PEG/PPG-20/5 PEG/PPG-20/5Dimethicone、Methoxy PEG/PPG-25/4 Dimethicone、Caprylic/Capric Triglyceride、Sodium Polyacrylate、Phenoxyethanol、o-Cymen-5-ol、Xanthan Gum、Potassium Hydroxide, Heat-killed L. plantarum powders (1x10\^9 cells/ g-cream)

Emulsion baseOTHER

Eligibility

Sex: ALLMin age: 20 YearsMax age: 60 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Healthy volunteers between the ages of 20-60. Exclusion Criteria: * Subjects with photosensitivity (Sun allergy). * Subjects are undergoing medical therapy for skin diseases. * Subjects with severe hyperpigmentation. * Subjects with diabetes. * Subjects with cosmetics allergy. * Subjects who have recently participated laser therapies or other treatments are not suitable for sun.

Locations (1)

Chia Nan University of Pharmacy and Science

Tainan, Taiwan

Outcomes

Primary Outcomes

Skin Diagnosis

The changes of skin condition by VISIA Complexion Analysis System

Time frame: Baseline, 4 weeks and 8 weeks

Secondary Outcomes

Skin Moisture

The changes of skin moisture by Skicon-200EX and Corneometer CM 825

Time frame: Baseline, 4 weeks and 8 weeks

Skin Color

The changes of skin color by DermaSpectrometer

Time frame: Baseline, 4 weeks and 8 weeks

Data from ClinicalTrials.gov

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