Since its introduction, robot-assisted radical prostatectomy (RARP) have become the standard surgical approach for the treatment of prostate cancer in the United States and then in Europe. Continuous refinements of surgical technique has been described in order to maximise outcomes while minimizing morbidities. The management of DVC is a crucial steps during RARP. It could be done prior or after its transection thanks to haemostatic effects of the pneumoperitoneum. This topic has been already investigated by some authors. However, no high quality evidence is available to opt in favour of either of the two approaches. Findings about estimated blood loss, positive surgical margins and urinary recovery differ among these studies and only one is a randomized controlled trial in a laparoscopic setting with a limited number of patients. Therefore, our objective was to evaluate in a prospective randomised setting whether a delayed ligation of the dorsal vascular complex impacted on perioperative, functional and oncological outcomes as compared to preventive ligation during robot-assisted radical prostatectomy.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
226
Ligation of the dorsal vascular complex during robot-assisted radical prostatectomy
Clinical Department of Urology, university Hospital Spedali Civili di Brescia
Brescia, Italy
Intraoperative estimated bool loss
Time frame: intraoperative
Transfusion rate
Time frame: 30 days from surgery
Overall positive surgical marigins
Time frame: intraoperative
Apical positive surgicals margins
Time frame: intraoperative
1-month continence
0 or 1 security pad per day
Time frame: 30 days from surgery
1-month PSA
Time frame: 30 days from surgery
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