Colorectal cancer is a maior cause of morbidity and mortality worldwide.Colonoscopy and removal of all adenomas is the most efficient method to prevent colorectal cancer.The most colorectal polyps detected are small(\<10mm) and diminutive(≦5mm) during colonoscopy.At that size,the are overwhelmingly hyperplastic or adenomatous,and rarely harbour high-grade dysplasia,cancer or sessile serrated adenoma/polyp.Traditional white-light endoscopy cannot reliably distinguish between small adenomatous and hyperplastic polyps,thus,real-time recognition of the polyp histology during colonoscopy has the potential to minimize both the costs and complications associated with endoscopic biopsy and polpectomy.Linked color imaging(LCI),a new system for endoscopy modality,creates clear and bright endoscopic images by using short-wavelength narrow-band laser light combined with white laser light on the basis of magnifying blue laser imaging(BLI) technology. it is easier to recognize a slight difference in color of the mucosa. This is a study to investigate the impact of Linked color imaging endoscopes on the in vivo histology prediction of colonic polyps.
This is a prospective study comparing the accuracy of linked color imaging(LCI) and standard white light colonoscopes in the diagnosis of small and diminutive colorectal polyps.
Study Type
OBSERVATIONAL
Enrollment
300
examination of the surface patterns and colors of polyps using Linked color imaging and white-light
Affiliated Hospital to Academy of Military Medical Sciences
Beijing, Beijing Municipality, China
RECRUITINGAffiliated Hospital to Academy of Military Medical Sciences
Beijing, Beijing Municipality, China
RECRUITINGthe accuracy of predicted in vivo polyp histology
the accuracy of predicted in vivo polyp histology
Time frame: 5 months
Sensitivity
Sensitivity of white light endoscopy in predicting histology
Time frame: 5 months
specificity
sensitivity of white light endoscopy in predicting histology
Time frame: 5 months
Sensitivity
Sensitivity of LCI endoscopy in predicting histology
Time frame: 5 months
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