The purpose of this study is to investigate the impact of follicular flushing on fertilization rate in women undergoing IVF treatment
This will be a prospective observational study on the effect of follicular flushing on fertilization rate in women undergoing IVF treatment. Oocytes from each woman will be allocated to one of three groups, depending on the aspirate or flush they are recovered from: Group I= egg retrieved in the follicular fluid of the first aspirate (no flushing) Group II= egg retrieved in the 1st-2nd flush Group III= egg retrieved in the 3rd-5th flush development and utilization. Pregnancy rates will be reported as a surrogate outcome.
Study Type
OBSERVATIONAL
Enrollment
60
All eggs will be fertilized by ICSI
Eugonia
Athens, Greece
RECRUITINGFertilization rate
Number of fertilized eggs per oocyte retrieved
Time frame: Day 1 post oocyte retrieval
Maturation rate
Number of mature (MII) eggs per oocyte retrieved
Time frame: Day of oocyte retrieval
Good quality embryos
Number of good quality embryos on Day 2
Time frame: Day 2 post oocyte retrieval
Blastocyst formation rate
Number of blastocysts on Day 5 per fertilized egg
Time frame: Day 5 post oocyte retrieval
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