Preoperative Corneal Thickness and Postoperative Visual Outcomes After Posterior Lamellar Corneal Transplant

Centre Hospitalier Régional Metz-Thionville113 enrolled

Overview

To evaluate the impact of preoperative corneal thickness on visual outcomes following Descemet's stripping endothelial keratoplasty (DSAEK) or Descemet membrane endothelial keratoplasty (DMEK)

Patients underwent DSAEK or DMEK for endothelial dysfunction, from October 2013 to November 2016. Patients aged \> 18 years and with an indication for posterior lamellar graft surgery, such as Fuchs dystrophy, were included. Exclusion criteria included a history of penetrating keratoplasty in the study eye and a need for a penetrating keratoplasty following endothelial graft failure. Visual acuity, central corneal thickness (CCT) and graft thickness were measured preoperatively, and at postoperative day 7 and months 1, 3 and 6.

Study Type

OBSERVATIONAL

Enrollment

113

Conditions

Corneal Changes of Membranes

Eligibility

Medical Language ↔ Plain English

Inclusion Criteria: * Clinically indicated need for posterior lamellar graft surgery (DSAEK or DMEK) such as: * Fuchs dystrophy, * pseudophakic bullous decompensation * or other endothelial dysfunction corneal Exclusion Criteria: * were a history of penetrating keratoplasty in the indicated eye * the technical inability of preoperative CCT measurement * the need for a penetrating keratoplasty following endothelial graft failure * severe postoperative complications resulting in unquantifiable visual acuity

Outcomes

Primary Outcomes

Descemet's stripping endothelial keratoplasty (DSAEK) or Descemet membrane endothelial keratoplasty (DMEK)

LogMar

Time frame: month 6

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.