This study will test the use of a new handheld device (called the N-Tidal C), that measures a person's tidal breath carbon dioxide, in diagnosing the cause of someone's breathlessness. It will also evaluate whether this device can detect when a person's breathing problem is getting worse.
When a person breathes out, they exhale carbon dioxide (CO2). The CO2 levels in breath change as they breathe out and this makes a specific pattern, or "waveform". This waveform can tell a clinician a lot about the underlying health of a person. There are disease specific CO2 waveforms for common breathing conditions such as Asthma and Chronic Obstructive Pulmonary Disease (COPD). However up until this point there has been no accurate and non-invasive method of measuring the tidal breath CO2 waveform. This study will test the N-Tidal C, a new handheld device that accurately measures this waveform, and whether it can differentiate different causes of breathlessness; namely asthma, heart failure, pneumonia, breathing pattern disorders and motor neurone disease.
Study Type
OBSERVATIONAL
Enrollment
70
Portsmouth Hospitals NHS Trust
Portsmouth, Hampshire, United Kingdom
The tidal breathing carbon dioxide waveform for each of the breathing conditions as measured by the N-Tidal C device
Time frame: 12 months
Change in the Tidal Breathing carbon dioxide waveform over time
Change in the tidal breathing carbon dioxide waveform, in each disease, over the 6 months.
Time frame: Change measures - baseline to 6 months
Disease Control in asthma patients
The Asthma Control Questionnaire Score for the Asthma patients
Time frame: 12 months
Disease Improvement in Breathing Pattern Disorder patients
The Nijmegen Questionnaire Score
Time frame: 12 months
Disease severity in the pneumonia patients
The CURB-65 Score
Time frame: 2 days
Disease severity in heart failure patients
The Trans Thoracic Echocardiogram (TTE) result
Time frame: 12 months
Hypercapnia in the motor neurone disease patients
The level of partial pressure carbon dioxide (pCO2)
Time frame: 12 months
Usability of the N-Tidal C device
Measured by how frequently the patients remember to use the N-Tidal C device over 6 months
Time frame: Change measures - baseline to 6 months
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Acceptability of the N-Tidal C device
Measured by a questionnaire of the participants experience of the device at the end of the study
Time frame: 12 months