German Stroke Registry - Endovascular Treatment

Universitätsklinikum Hamburg-Eppendorf10,000 enrolled

Overview

The German Stroke Registry (GSR) Endovascular Treatment is an academic, independent, prospective, multicentre, observational registry study. Consecutive patients treated with endovascular stroke treatment will be enrolled in German stroke centers. Patients receive regular care and data will be collected as part of clinical routine. Baseline clinical and procedural information as well clinical follow-up information during in-hospital stay, and up to 90 days of stroke onset are collected. Data collected include demographics, National Institute of Health Stroke Scale (NIHSS) on admission, pre-treatment ASPECTS, information on timing and success of interventional treatment, procedural complications, intracranial hemorrhage, and functional outcome.

Study Type

OBSERVATIONAL

Enrollment

10,000

Conditions

Acute Ischemic Stroke

Interventions

telephone call d90OTHER

telephone call on day 90 to assess the primary outcome (mRs d90)

Eligibility

Medical Language ↔ Plain English

Inclusion Criteria: * Clinical diagnosis of acute ischemic stroke * Eligible for intravenous thrombolysis (IVT) and IVT initiated within 4.5 hours after stroke onset * Confirmed diagnosis of persistent occlusion of terminal carotid artery, middle cerebral artery (M1 or M2), or basilar artery consistent with symptoms * Age \>18 years * Ethic approval in process Exclusion Criteria: none

Outcomes

Primary Outcomes

modified Ranking Scale (mRS) on day 90

The scale is a commonly used measurement for the degree of disability or dependence in the daily activities of people who have suffered a stroke; scale range 0-6; with 0 - No symptoms. 1 - No significant disability. Able to carry out all usual activities, despite some symptoms. 2 - Slight disability. Able to look after own affairs without assistance, but unable to carry out all previous activities. 3 - Moderate disability. Requires some help, but able to walk unassisted. 4 - Moderately severe disability. Unable to attend to own bodily needs without assistance, and unable to walk unassisted. 5 - Severe disability. Requires constant nursing care and attention, bedridden, incontinent. 6 - Dead. publication: van Swieten J, Koudstaal P, Visser M, Schouten H, et al. (1988). "Interobserver agreement for the assessment of handicap in stroke patients". Stroke. 19 (5): 604-607. doi:10.1161/01.str.19.5.604. PMID 3363593.

Time frame: 90 days

Central Contacts

Maximilian Schell

CONTACT

+49 (0)1522/2834807 m.schell@uke.de

Götz Thomalla, Prof. Dr. med.