Correlation of Two Methods for Cough Peak Flow Measurement in Intubated Patients

Centre Hospitalier Régional d'Orléans62 enrolled

Overview

Cough Peak Flow (CPF) seems to be an efficient tool to assess cough capacity for the intensive care unit (ICU) ventilated patient. CPF can be used in the ventilator weaning process, as reflecting the upper airways protection capacity. CPF requires disconnection of the patient from the ICU ventilator, supplemental material (handheld spirometer, antibacterial filter) and an excellent synchronization between the specialized caregiver and the patient. We aimed that CPF with the ventilator built-in flow-meter is correlated with CPF using a handheld flowmeter connected to the endotracheal tube.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Respiratory Insufficiency Ventilator Weaning

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age \> 18 years * Mechanically ventilated patient \> 24 hours * Weaning ventilator phase (PEEP \< 9 cmH2O and Support \< 15 cm H2O) * Richmond Agitation Sedation Scale between -1 and +1 * Patient's agreement to participate Exclusion Criteria: * Pregnant women * Bronchospasm * FiO2 \> 70% * Thoracic surgery \< 7 days * Abdominal surgery \< 7 days * Thoracic injury with rib fracture \< 21 days * Pneumothorax \< 24 hours

Locations (1)

Outcomes

Primary Outcomes

Correlation coefficient for the two CPF assessment methods, on extubation day

Time frame: Within 1 hour before mechanical ventilation termination (extubation)

Secondary Outcomes

Discriminatory power of CPF to predict successful weaning of mechanical ventilation, i.e. no reintubation within 72 hours after extubation, or unsuccessful weaning.

Thresholds of CPF will be tested as predictors of weaning success

Time frame: During the mechanical ventilation until 72 hours post extubation

Assess the correlation between CPF and length of mechanical ventilation

Time frame: During the mechanical ventilation until 72 hours post extubation

3. Correlation between the two CPF assessment methods the days before extubation

3\. Correlation between the two CPF assessment methods the days before extubation

Time frame: During the mechanical ventilation until 72 hours post extubation