Closed-loop Anaesthesia for Liver Transplantation: a Pilot Study

Hopital Foch12 enrolled

Overview

Automated titration of propofol and remifentanil guided by the bispectral index (BIS) has been used for numerous surgical procedures. Orthotopic liver transplantation (OLT) uniquely combines major volaemic changes, an anhepatic phase, and ischaemia-reperfusion syndrome. We assessed the behaviour of this automated controller during OLT

Study Type

INTERVENTIONAL

Allocation

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Anesthesia Liver Transplant

Interventions

Automated titration of propofol and remifentanilDEVICE

Calculation of Consumption of propofol and remifentanil

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: Patients scheduled for OLT Exclusion Criteria: age younger than 18 years, pregnancy, allergy or hypersensitivity to propofol or remifentanil, a medical history of psychiatric illness, and supraspinal neurological disorders

Locations (1)

Hopital Foch

Suresnes, France

Outcomes

Primary Outcomes

percentage of time spent in the BIS interval [40-60]

Time frame: 1 day

Data from ClinicalTrials.gov

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