Inflammation and Steatosis: the Role of Alpha-defensin

Hillel Yaffe Medical Center50 enrolled

Overview

The aim of this study is to examine the correlation between the severity of non-alcoholic steatohepatitis/non alcoholic fatty liver disease (NASH/NAFLD) in naïve and hepatitis C (HCV) positive patients and the amplitude of alpha-defensin immunohistochemical staining in liver biopsy.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Inflammation Fatty Liver

Interventions

Immunohistochemical stainingDIAGNOSTIC_TEST

Pathological liver slides to be immunohistochemically stained for alpha-defensin

Eligibility

Sex: ALLMin age: 15 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Fatty liver disease patients with liver biopsy Exclusion Criteria: * None

Locations (1)

Hille Yaffe Medical Center

Hadera, Israel

Outcomes

Primary Outcomes

Amplitude of immunohistochemical stain

The amplitude of each slide will be graded from 1-4

Time frame: Six months

Central Contacts

Rami Abu Fanne, MD

CONTACT

972-50-3573694 ramia@hadassah.org.il

Data from ClinicalTrials.gov

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