Aim of the study is to investigate the impact of energy flux (achieved by changes in physical activity) under the conditions of energy balance, caloric restriction and overfeeding in healthy subjects.
A low energy flux is achieved by low energy expenditure, equivalent to low physical activity and with a corresponding low energy intake. A high energy flux is achieved by high energy expenditure, equivalent to high physical activity and with a corresponding high energy intake, respectively. The protocol of this randomized, intra-individual nutrition intervention includes 12 one-day interventions with 3 different levels of energy flux and 4 different diet conditions.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Enrollment
16
3 different levels of physical activity
4 different types of energy intake
Institute of Nutritional Medicine, University of Hohenheim
Stuttgart, Germany
energy balance
difference between predefined energy balance and measured energy balance
Time frame: 24 hours
ghrelin levels
area under the curve of total plasma ghrelin
Time frame: every 2 hours during the day over 14 hours
arterial stiffness
pulse wave velocity
Time frame: 15 hours
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