Although many reports have investigated the relationship between subfertility and uric acid levels in semen, to the best of author knowledge, there is no study have been published to yet focus on the effects of asthenospermia treatments, such as given an oral zinc supplementation, on the activity of urate-related enzymes, which are important in fertility of human.
The present study was designed to investigate the effect of zinc supplementation on the qualitative and quantitative characteristics of semen, along with uric acid levels and urate-related enzymes in the seminal plasma and spermatozoa of asthenospermic males.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
120
The subfertile group treated with zinc sulfate, every participant took two capsules of zinc sulfate per day for three months (each one 220 mg).
Mahmoud Hussein Hadwan
Hillah, Babylon, Iraq
Measurement the uric acid level in spermatozoa and seminal plasma by using spectrophotometer.
Clinical parameter
Time frame: up to three months.
Measurement the adenosine deaminase activity in spermatozoa and seminal plasma by using spectrophotometer.
Enzyme
Time frame: up to three months.
Measurement the xanthine oxidase activity in spermatozoa and seminal plasma by using spectrophotometer.
Enzyme
Time frame: up to three months.
Measurement the 5'-nucleotidase activity in spermatozoa and seminal plasmaby using the spectrophotometer.
Enzyme
Time frame: up to three months.
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.