Safety and Efficacy of LMWH Versus Rivaroxaban in Chinese Patients Hospitalized With Acute Coronary Syndrome

Inclusion Criteria: * Male or female aged ≥ 18 years * Diagnosed with ACS (STEMI, NSTEMI, unstable angina) * With an indication for short-term combination use of DAPT and enoxaparin. Exclusion Criteria: * Already received thrombolytic therapy or revascularization or needing revascularization therapy in 12 hours. * With platelet glycoprotein IIb/IIIa receptor antagonist therapy. * With increased bleeding risk, such as but not limited to, active internal bleeding, clinically significant bleeding, bleeding at a non-compressible site, or bleeding diathesis within 30 days of randomization; platelet count less than 90,000/μL at screening; intracranial hemorrhage; major surgery, biopsy of a parenchymal organ, or serious trauma within 30 days before randomization; clinically significant gastrointestinal bleeding within 12 months before randomization; an international normalized ratio known to be\>1.5 at the time of screening; abciximab bolus or infusion within the preceding 8 hours, or an eptifibatide or tirofiban bolus or infusion within the past 2 hours preceding randomization; or any other condition known to increase the risk of bleeding. * Severe concomitant condition or disease, such as cardiogenic shock at the time of randomization, ventricular arrhythmia refractory to treatment at the time of randomization, calculated creatinine clearance b 30 mL/min at screening, known significant liver disease (e.g., acute hepatitis, chronic active hepatitis, cirrhosis), or liver function test abnormalities (confirmed with repeat testing) which would require study drug discontinuation, i.e., aminoleucine transferase (ALT) \>5 × the upper limit of the normal range (ULN) or ALT \>3 × ULN plus total bilirubin \>2 × ULN, prior ischemic stroke or transient ischemia attack, anemia (i.e., hemoglobin \< 10 g/ dL＝ at screening, known clinical history of human immunodeficiency virus infection at screening, substance abuse (drug or alcohol) problem within the previous 6 months or any severe condition such as cancer that would limit life expectancy to less than 6 months. * With an indication for long-term oral anticoagulation therapy such as atrial fibrillation, venous thromboembolism, or prior placement of a mechanical heart valve. * With other contraindications for use of rivaroxaban and enoxaparin. * Enrolled in another clinical study.