The aim of this study is to determine the efficacy of turmeric and tulsi polyherbal formulation in the management of frailty in the elderly population.
Frailty is a wasting syndrome of old age that leaves a person vulnerable to falls, functional decline, morbidity and mortality. Reducing the severity of frailty will provide large benefits for individuals, their families and for the society. It is assumed that early intervention with frail people will improve quality of life and reduce the costs of care. This trial is testing the frailty intervention with herbal medicine. If this frailty intervention is shown to be effective, there are major potential benefits to the frail older population generally in terms of decreased disability. The interventions being examined are readily transferable to routine clinical practice and can potentially be applied routinely in aged care services.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
50
Polyherbal formulation along with standard of care
Usual standard of care for consist of exercise, caloric and protein support, vitamin D, reduction of polypharmacy along with medical management of health condition, assessment of care needs and provision of care. These will be determined on case by case basis by research clinician.
Mazumdar Shaw Medical Centre
Bangalore, Karnataka, India
Frailty Score
To assess a change in frailty score from baseline in 3 months between two groups
Time frame: 3 months
C reactive protein
Change in C-reactive Protein (CRP) from baseline
Time frame: 3 months
Frequency of falls
defined as an event resulting in a person coming to rest unintentionally on the ground or other lower level; near-falls would not be included
Time frame: 3 months
Health service utilization
frequencies of doctor visits, emergency room visit, hospitalization, nursing home admission
Time frame: 3 months
Mortality
Death of study participant during study period
Time frame: 3 months
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