To observe the effect of sevoflurane on the concentration of S100β and regional cerebral oxygen saturation in infants with congenital heart disease undergoing cardiac surgery.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
100
1.5%-3% Sevoflurane will be given during the cardiac surgery except cardiopulmonary bypass.
Beijing Anzhen Hospital
Beijing, Beijing Municipality, China
RECRUITINGConcentration of S100β protein
The concentration of S100β protein was performed using the electrochemiluminescence immunoassay.(Blood samples from patients were drawn from central intravenous.)
Time frame: 5 minutes after tracheal intubation; immediately after cardiopulmonary bypass; immediately after operation; 12 hours, 24 hours postoperative
Level of regional cerebral oxygen saturation(rScO2)
The rScO2 was measured by using noninvasive near-infrared spectroscopy during cardiac surgery
Time frame: 5 minutes after tracheal intubation; immediately after cardiopulmonary bypass; immediately after operation; 12 hours, 24 hours postoperative
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