Efficacy of Natural Seawater Based Throat Spray in Acute Sore Throat Relief

Inclusion Criteria: * 1\. Adults (male or female) aged ≥ 18 years old. * 2\. Patients with complaint of sore throat ≤ 72h. * 3\. Sore throat exclusively due to upper respiratory tract infection (tonsillitis, pharyngitis, rhinopharyngitis). * 4\. Clinical confirmation by the physician for the presence of typical signs (spontaneous pain, local inflammation) of acute pharyngitis or tonsillitis. * 5\. Pain intensity scored by patient on the 5-point descriptive pain intensity scale as slight, mild or moderate. * 6\. Willingness to provide written informed consent prior to perform of any study related procedure. * 7\. Subjects agreeing to follow the study requirements during the whole study period (including forbidden medication and food supplements). * 8\. Subjects agreeing not to modify their lifestyle habits during the whole study period (diet, physical activity). * 9\. Subject affiliated to social security. * 10\. Subject able to understand verbal and written local language and in capacity to fill-in patient diary by himself/herself. Exclusion Criteria: * 1\. Previous history of allergy or known intolerance to one of the following formulation ingredients: seawater, vegetable glycerin, mint, lemon, acacia honey, propolis, essential oils. * 2\. Active Smokers. * 3\. Fever \> 38°C at randomization. * 4\. Past or current throat phlegmon. * 5\. Past or current seasonal allergy. * 6\. Past or current asthma. * 7\. Past or current chronic rhinosinusitis. * 8\. Past or current chronic obstructive pulmonary disease (COPD). * 9\. Past or current ENT (Ear, Nose and Throat) cancer. * 10\. Acute rhinosinusitis. * 11\. Controlled or uncontrolled diabetes. * 12\. Gastroesophageal reflux disease (GERD). * 13\. Known immunodeficiency. * 14\. Any painful condition that may distract attention from sore throat pain (ex: mouth ulcers etc.) or that requires analgesic usage. * 15\. Any disease that may interfere with the study aim from investigator's opinion. * 16\. Evidence of mouth breathing or severe coughing. * 17\. Patient with severe pain intensity on 5-point descriptive pain intensity scale. * 18\. Subjects taking: * chronic treatment for throat or other ENT pathology, * current antibiotherapy or stopped less than 2 weeks before inclusion, * chronic treatment (\>3 months) with local or systemic corticotherapy, or immunotherapy, * local or systemic antihistaminic. * 19\. Subjects refusing to stop at entry into the study: * throat spray, lozenge, pastille, * local throat or systemic analgesic, * medicated confectionary, * nasal wash and spray, * nasal corticosteroid or antihistaminic nasal spray, * medication to gargle, * honey, propolis, or any sore throat home remedies. * 20\. Known liver disease or hypersensitivity to paracetamol. * 21\. Pregnant, breastfeeding or seeking pregnancy women. * 22\. Positive result from rapid strep throat test. * 23\. Subjects already included once in this study. * 24\. Subjects participating in another clinical trial or in the exclusion period to another study. * 25\. Subjects having a member of his/her home who is currently participating to this study.