Assessing Cement-bone Incorporation and Adjacent Segment Degeneration Following Cement Augmentation; an MRI-PET Follow-up

Inclusion criteria * Men and women aged 18 to 70 years * Minimum 3-year follow-up * Single-level vertebral kyphoplasty * Index surgery at UniversitätsSpital Zürich * MRI-scan during initial treatment * Informed consent provided Exclusion criteria * Combined with other operative procedure on the spine (e.g. dorsal instrumentation) * Intraoperative intradiscal cement leakage * Previous history of spinal surgery except on the cervical spine * Metastatic disease with skeletal involvement * Known chronic diseases of the bone metabolism other than osteoporosis * Documented pregnancy (see also 6.3) * Presence of implants not suited for MRI (pacemaker, neuro-stimulators, pain pumps, insulin pumps, Cochlea implants, metallic foreign bodies like bullet fragments)