The aim of this study is to perform a randomized controlled trial for patients undergoing bariatric surgery, comparing the need for opiates with and without administration of a transversus abdominis plane (TAP) block using the long acting local anesthetic, liposomal bupivacaine (Exparel®). From this study, the investigators will assess whether use of long acting local anesthetic can reduce the need for opiates in the bariatric population.
A prospective randomized controlled trial investigating the use of long acting local anesthetic for transversus abdominis block in patients undergoing bariatric surgery at Montefiore Medical Center. Patients will be randomized to either receive an intraoperative TAP block with LB, an intraoperative TAP block with RB, or no TAP block. All participants will receive standard post-operative analgesia regimen. Pain scores will be recorded by the nursing staff as reported by the patients for 24-36 hours post surgery. Patients will be monitored for secondary post-operative complications up to the 2-week mark following intervention.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
219
Infiltration of the transverse abdominis peritoneum by a local anesthetic under laparoscopic visualization.
Infiltration of the transverse abdominis peritoneum by a local anesthetic under laparoscopic visualization.
Montefiore Medical Center
The Bronx, New York, United States
Fentanyl PCA mcg
Fentanyl PCA (patient controlled analgesia) total microgram usage.
Time frame: 24 hours post surgery.
Total Fentanyl Usage
Total fentanyl usage in micrograms, including both PCA and IV push administered medication.
Time frame: During hospitalization, up to 7 days.
Acetaminophen Usage
Total amount of acetaminophen used for analgesia.
Time frame: During hospitalization, up t 7 days.
NSAID Usage
Total amount of NSAID (ketorolac) use for analgesia.
Time frame: During hospitalization, up to 7 days.
Pain Score
Patient reported composite measure pain score, with a total range of 0 to 10, with 0 being the absence of pain, 1 being the least amount of pain and 10 being the highest amount of pain.
Time frame: 24 hours post surgery.
Length of Stay
Hours of hospitalization post-surgery
Time frame: Assessed every 24 hours post surgery, up to 168 hour post-surgery.
Nausea
Number of participants with presence or absence of nausea reported and recorded by the nurse.
Time frame: 24 hours post surgery.
Time to Ambulation
Time frame: Assessed every 24 hours post surgery, up to 168 hour post-surgery.
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.