The Midline catheter is a peripherally-inserted catheter, with the distal tip being placed at or below the level of the axilla. It is a relevant alternative to other catheters in case of limited venous access and long-run perfusions. Moreover, another significant advantage may be the reduction of the risk of infection. However, the Midline catheter is poorly described in scientific literature, essentially through retrospective and meta analyses including multiple types of catheters (Piccline, CVC, PAC). Therefore, the TIM-GHM study aims to prospectively assess the rate of infections in case of the Midline catheter. The results of this study could bring a collective benefit in terms of knowledge and reliability of these intravascular devices. Depending on these results, a randomized, controlled study will be considered, in order to compare the Midline catheter to its main alternative : the Piccline.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
OTHER
Masking
NONE
Enrollment
250
The catheter will be inserted according to usual practices, after the enrollment of the patient in the study. The follow-up will last until the removal of the catheter, which will also be done according to usual practices. Following the removal, bacteriologic analyses will be performed in order to diagnose any prospective infection.
Groupe Hospitalier Mutualiste de Grenoble
Grenoble, France
Incidence of infection of midline catheter
The method used for bacteriologic analyses will be the Brun Buisson Technique. The diagnosis of infection of the catheter will be based on the clinical signs, the catheter bacteriology, the blood culture collected on the patient and the blood culture collected on the catheter.
Time frame: Catheter removal, performed up to 28 days after enrollment
Identification of the germs responsible for infections of midline catheter
For each infected catheter, the species name of the germ responsible for the infection will be collected.
Time frame: Catheter removal, performed up to 28 days after enrollment
Identification of intravenous treatments - Corticosteroid
Determination of whether corticosteroid are intravenously administered during the day (YES/NO).
Time frame: Everyday from baseline, up to 28 days
Identification of intravenous treatments - Antibiotics
Determination of whether antibiotics are intravenously administered during the day (YES/NO).
Time frame: Everyday from baseline, up to 28 days
Identification of intravenous treatments - Chemotherapy
Determination of whether chemotherapy was intravenously administered during the day (YES/NO).
Time frame: Everyday from baseline, up to 28 days
Identification of intravenous treatments - Nutrient solution
Determination of whether nutrient solution was intravenously administered during the day (YES/NO).
Time frame: Everyday from baseline, up to 28 days
Duration of insertion procedure
Time frame: Baseline
Lifetime of catheter
Time from catheter insertion to catheter removal, measured in days.
Time frame: Catheter removal, performed up to 28 days after enrollment
Body Mass Index
Time frame: Baseline
White blood cells count
Time frame: Everyday from baseline, up to 28 days
Incidence of thrombosis
If the catheter is no more permeable, a doppler echocardiography will be done to confirm the diagnosis of thrombosis.
Time frame: Catheter removal, performed up to 28 days after enrollment
Patient comfort
Numeric rating scale will be collected for each of these 3 dimensions : comfort when eating, comfort when moving, comfort for personal hygiene The scale will range from 0 to 10. 0 will mean "very uncomfortable" and 10 will mean "very comfortable".
Time frame: Every three days from baseline, up to 28 days
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.