The hypothesis tested in this clinical trial is that a biomimetic synthetic bone graft substitute (MimetikOss, Mimetis Biomaterials) with similar properties to those of human bone can reach a clinical outcome non inferior to that of a deproteinized bovine bone matrix bone graft substitute (Bio-Oss, Geistlisch) in an alveolar ridge preservation procedure followed by implant placement in terms of bone volume changes (primary end point), bone histological observation implant stability and bone level changes (secondary end points).
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
102
Ridge preservation bone grafting after dental extraction.
Ridge preservation bone grafting after dental extraction.
Universidad de los Andes
Santiago, Chile
IOC Dental Clinic
Vecindario, Las Palmas de Gran Canaria, Spain
Universitat Internacional de Catalunya
Barcelona, Spain
Universidad de granada
Granada, Spain
Bone volume changes
Bone ridge horizontal and vertical change assessment by CBCT
Time frame: 6 months post grafting procedure
Bone histological observation
Histomorphometric analysis of the tissue components
Time frame: 6 months post grafting procedure
Implant survival
ISQ measurement and bone level changes analysis
Time frame: 4 months y 1 year post grafting procedure
Implant survival
Bone level changes analysis
Time frame: 4 months y 1 year post grafting procedure
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Clinica dental Triana
Las Palmas de Gran Canaria, Spain
Clínica Bustillo
Pamplona, Spain
Universitat de Sevilla, Facultad de odontología
Seville, Spain
Universidad de Valencia, Facultad de Medicina y Odontología
Valencia, Spain