Prostate cancer is the most common cancer in men over 50 years old and the third leading cause of cancer death. Because of the variety of prostate cancers, different treatments exist. Several criteria guide this management in daily practice: PSA level; TNM stage (digital rectal examination, trans-rectal ultrasound and classical visual imaging) and pathological differentiation with the Gleason score, to which can be added other prognostic criteria: growth and doubling time of the serum PSA, number of positive biopsies and percentage of cancer lesions by biopsy. Functional imaging by PET and MRI is increasingly used in daily clinical practice to characterize prostate cancer, either during initial discovery or during recurrence. In this context, it is the qualitative visual analysis that is mainly used. Quantitative image analysis could add new criteria to guide patient management. Consequently, the objective of this study were: * Optimization of 18F-choline PET/CT Acquisition in Prostate Cancer * Comparison the quantitative parameters obtained by 18F-Choline PET / CT and both perfusion MRI and histological parameters.
Study Type
OBSERVATIONAL
Enrollment
61
CHRU de Brest
Brest, France
correlation between Gleason score and dynamic parameters on PET and MRI
study the potential correlation between dynamic parameters on PET and MRI
Time frame: when anatomopathological report is available, an average of 3 months after the PET/CT
reconstructions on 18F-choline PET
determine the mean influx from each reconstruction which is the closest to the objective value
Time frame: when all 18F-choline PET are performed, an average of 6 months
best "fitting" on PET and MRI
the Akaike Criteria Information was chose to choose the best fit
Time frame: when all MRI are performed, an average of 6 months
comparison between data (PSA, TNM stage, EFS and OS)
comparison between data (PSA, TNM stage, EFS and OS)
Time frame: 01/05/2017
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